Exchange 2003

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NDR "550 5.7.1 Submission has been disabled for this account" during migration from Exchange 2003 to 2010

Here's an interesting issue you may run into when migration from Exchange 2003 to Exchange 2010.   E-mails passing through the Exchange 2010 Hub Transport role may bounce back with a Non-Delivery Report (NDR) with the SMTP code 550 5.7.1 that says something like "Submission has been disabled for this account."

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